Copious vaginal discharge finally diagnosed as cervical adenocarcinoma: A case report

Author:

Mao Peiyu1ORCID,Zhang Chen1,Wang Xinyan1,Yang Huadi1ORCID

Affiliation:

1. Department of Gynecology and Obstetrics, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Abstract

Rationale: Copious vaginal discharge is a frequent manifestation of reproductive tract infections. However, when little effect can obtain treated as vaginitis, cervical disease should be highly suspected. Patient concerns: A 41-year-old woman had suffering from abnormally increased vaginal discharge without any other signs of discomfort for the past 4 years. A lot of medical examinations and treatment of vaginosis were administered, resulting in unclear diagnosis and little effect. Diagnoses: Cervical adenocarcinoma. Interventions: Gynecological examination, vaginal microbiome culture, and primary cervical cancer screening were negative, and a positron emission tomography revealed an increased 18F-fluorodeoxyglucose metabolism in the local cervix. After a thorough description, the patient demanded a hysterectomy and bilateral salpingo-oophorectomy. Outcomes: Histopathological evaluation confirmed adenocarcinoma in situ of the uterine cervix. Lessons: The correct diagnosis of symptomatic patients with increased vaginal discharge is challenging. Human papillomavirus-negative patients presenting profuse watery vaginal discharge with an abnormal signal of cervix lesion on positron emission tomography or magnetic resonance imaging should be alert to cervical adenocarcinoma. Deep-seated cervical biopsy, conization, or even hysterectomy is conducive to early diagnosis, treatment and improvement of prognosis.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

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