Cervical metastasis of breast cancer: A case report and literature review

Abstract

Rationale: Cervical metastasis of breast cancer is rare and its clinical manifestations are similar to those of primary cervical cancer. It is thus easy to misdiagnose, with diagnosis mainly depending on pathology and immunohistochemistry. There have been few studies on its treatment and there is thus no standard treatment plan. Patient concerns: This is a 64-year-old female patient presented with a 2-month history of abnormal postmenopausal vaginal discharge, who had previous history of breast cancer. Diagnoses: Based on the gynecological examination, imaging results, pathology, and immunohistochemical results, a diagnosis of metastatic carcinoma of the cervix and breast cancer was confirmed. Interventions: She received computed tomography-guided 3-dimensional high-dose-rate brachytherapy in combination with chemotherapy. Outcomes: She achieved complete response locally. This case provides a new local treatment option for patients with inoperable localized cervical metastases. Lessons: We hope that this report and the accompanying review help to enrich the literature pertaining to the treatment of rare cervical metastases, providing a foundation for the improved survival of affected patients.