Telocytes and inflammation: A review

Author:

Zhang Yuhua1ORCID,Tian Hu2ORCID

Affiliation:

1. The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Department of General Surgery, Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China

2. Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Key Laboratory of Metabolism and Gastrointestinal Tumor, Jinan, Shandong, China.

Abstract

Telocytes are a new type of interstitial cell with a diverse morphology and important functions, such as mechanical support, signal transduction, immune regulation, and tissue repair. In this paper, the origin and physiological and pathological functions of telocytes as well as their role in inflammation will be discussed, and the functions and targets of telocytes in inflammation will be fully reviewed, which may contribute to a new therapeutic strategy for inflammatory diseases in the future.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

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