Renal cortical necrosis – a rare manifestation of dengue fever: A case report

Author:

Rehman Fazal ur1,Rehan Syeda Tayyaba2,Yousaf Fatima1,Rathore Navin3,Rind Bakhtawar Jamal4,Mahmmoud Fadelallah Eljack Mohammed5ORCID,Asghar Muhammad Sohaib67,Omair Farruk8

Affiliation:

1. Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan

2. Dow University of Health Sciences, Karachi, Pakistan

3. Liaquat National Hospital and Medical College, Karachi, Pakistan

4. Jinnah Sindh Medical University, Karachi, Pakistan

5. University of Bakhtalruda Faculty of Medicine and Health Sciences, AL-Dewaym, Sudan

6. Department of Internal Medicine at Sun ’N Lake, AdventHealth, Sebring, FL

7. Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN

8. King Fahad Armed Forces Hospital, Jeddah, Kingdom of Saudi Arabia.

Abstract

Rationale: Dengue fever is a widespread mosquito-borne viral disease, most prevalent in the tropical and subtropical areas of the world. There has been a significant rise in the incidence and number of outbreaks of dengue in recent years, which has made it a matter of global concern. It may be associated with a number of renal complications, ranging from hematuria, proteinuria, glomerulonephritis, and acute tubular necrosis. However, renal cortical necrosis (RCN) is a rare renal complication of this disease. Patients concerns: We report the case of a young gentleman who presented with fever, vomiting, and anuria. On workup, he was found to be having complicated Dengue fever with RCN resulting in acute renal failure. Diagnosis: To the best of our knowledge, RCN is not a reported renal complication of dengue fever. Interventions and outcomes: Our report highlights the importance of early consideration of renal cortical necrosis in patients with dengue fever and persistent anuria. Lesson: This would allow for better disease prognostication while enabling physicians to develop more effective treatment strategies.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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