Clinical and individual factors of quality of life of chronic liver disease patients at University of Gondar comprehensive specialized hospital, Northwest Ethiopia 2022

Author:

Teshome Eliud1,Hailu Workagegnehu1,Adane Aynishet1,Belayneh Melese Endalkachew1,Abebaw Angaw Dessie1,Tarekegn Gebrekidan Ewnetu2ORCID

Affiliation:

1. Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia

2. Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Abstract

Chronic liver disease (CLD) may be a major cause of morbidity and mortality worldwide, as well as a reduction in health-related quality of life. In Ethiopia, however, little is known about the effect of CLD on quality of life. The purpose of this study was to evaluate CLD patients’ health-related quality of life and associated factors. A cross-sectional study was carried out on 227 CLD patients who were being followed up on at the University of Gondar specialized hospital between January 2022 and February 2022. To assess health-related quality of life, the chronic disease Questionnaire was used. Epi-Data version 4.6 was used to enter data, and SPSS version 25 was used for all statistical analysis. To identify factors associated with the outcome variable, a linear regression model was used. Patients with CLD had significantly lower mean scores in all domains of health-related quality of life. Hepatitis B virus treatments and a college education or higher have a positive effect on all domains of health-related quality of life. Upper gastrointestinal bleeding, spontaneous bacterial peritonitis (SBP), hepatic encephalopathy (HE), and ascites were a clinical related factors significantly associated with poor health-related quality of life in simple linear regression. In this study setting, all dimensions of health-related quality of life of patients with CLD were compromised. Antiviral treatment for HBV infection, beta-blocker treatment, and the presence of complications such as ascites were all found to be significantly related to health-related quality of life. This necessitates going above and beyond standard treatments to improve patients’ quality of life with CLD.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

Reference24 articles.

1. Development of a disease specific questionnaire to measure health related quality of life in patients with chronic liver disease.;Younossi;Gut,1999

2. Impact of chronic liver disease and cirrhosis on health utilities using SF-6D and the health utility index.;Dan;Liver Transplant,2008

3. Health-related quality of life in liver cirrhosis patients using SF-36 and CLDQ questionnaires.;Janani;Clin Exp Hepatol,2018

4. Chronic liver disease in Ethiopia: a clinical study with emphasis on identifying common causes.;Tsega;Ethiop Med J,1992

5. CDC in Ethiopia.;GLANCE;Global Health,2018

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