Efficacy of magnetic therapy for osteoporotic patients: A meta-analysis of randomized controlled studies

Abstract

Background: Magnetic therapy may have some potential in treating osteoporosis, and this meta-analysis aims to study the efficacy of magnetic therapy for osteoporotic patients. Methods: We have searched several databases including PubMed, EMbase, Web of Science, EBSCO and Cochrane library databases, and selected the randomized controlled trials comparing the efficacy of magnetic therapy for osteoporotic patients. This meta-analysis was conducted using the random-effect or fixed-effect model based on the heterogeneity. Results: Five randomized controlled trials were included in this meta-analysis. Compared with sham procedure in osteoporotic patients, magnetic therapy was associated with significantly increased bone mineral density (standard mean difference [SMD] = 2.39; 95% confidence interval [CI] = 0.27–4.51; P = .03), decreased pain scores (mean difference [MD] = −0.86; 95% CI = −1.04 to −0.67; P < .00001), and calcium (MD = −0.61; 95% CI = −0.92 to −0.29; P = .0002), but revealed no influence on phosphate (MD = 0.07; 95% CI = −0.30 to 0.44; P = .71), osteocalcin (SMD = 0.65; 95% CI = −2.87 to 4.17; P = .72), or ALP (SMD = −0.43; 95% CI = −0.92 to 0.07; P = .09). Conclusions: Magnetic therapy may be effective for the treatment of osteoporotic patients.