Nasal spindle cell tumor: A case report and literature review

Author:

Feng Yu12ORCID,Yu Yunbei3,Meng Kai4,Li Maocai1,Jia Guotao5,Du Yongya6,Liu Siyu17,Gong Lili1,Li Lianqing1

Affiliation:

1. Department of Otorhinolaryngology Head and Neck Surgery, Liaocheng People’s Hospital, Liaocheng, China

2. Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, China

3. Research Department of Liaocheng People’s Hospital, Liaocheng People’s Hospital, Liaocheng, China

4. Liaocheng Medical Insurance Fund Audit Center, Liaocheng, China

5. Department of Pathology, Liaocheng People’s Hospital, Liaocheng, China

6. Department of Otorhinolaryngology Head and Neck Surgery, Liaocheng Dongchangfu People’s Hospital, Liaocheng, China

7. Weifang Medical University, Weifang, China.

Abstract

Background: Spindle cell tumors are rare and can occur in any organ or tissue. Due to their rarity the clinicopathological features and diagnostic protocols have not been adequately studied. However, it has become necessary to develop differential diagnosis of spindle cell tumors. Here, we report a case of a nasal spindle cell tumor diagnosed at our hospital in attempt to contribute to this gap in literature. Key points from the case: A male in his 30s was admitted to our hospital with nasal obstruction that had persisted for several years. Electronic fibrolaryngoscopy revealed a smooth neoplasm within the nasal cavity. Main lessons to be learned from this case report: The results of this case emphasize that spindle cell tumors have large morphological variations, and it is difficult to determine the origin of tumor cells using hematoxylin and eosin staining alone. Therefore, it is necessary to improve the immunohistochemistry and combine it with clinical symptoms to diagnose the disease.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

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