Reversible leukoencephalopathy caused by 2 rodenticides bromadiolone and fluroacetamide

Author:

Lu Aili,Yuan Fang,Yao Yufei,Wen Wanxin,Lu Hongji,Wu Shibiao,Wang LixinORCID

Abstract

Abstract Rationale: With the easy access, rodenticide poisoning has been a public health problem in many countries. Characteristics of central nervous system (CNS) lesions induced by rodenticides are scarcely reported. Patient concerns: We presented a case of a 40-year-old man with seizure and consciousness disorder, coagulation dysfunction, and symmetric lesions in white matter and corpus callosum. Diagnosis: He was diagnosed with rodenticide poisoning due to bromadiolone and fluoroacetamide. Interventions: He was treated with vitamin K, hemoperfusion, acetamide, and calcium gluconate. Outcomes: His leukoencephalopathy was reversed rapidly with the improvement of clinical symptoms. Lessons: This report presented the impact of rodenticide poisoning on CNS and the dynamic changes of brain lesions, and highlighted the importance of timely targeted treatments.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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