Dietary intervention for adult survivors of cancers other than breast cancer: A systematic review

Author:

Matsumoto Hideo1ORCID,Onogawa Seiji2,Sonoi Norihiro3,Sagawa Masano4,Wakiyama Shigeki5,Ogawa Ryo6,Miyazaki Yasuhiro7,Nagata Shigeyuki8,Okabayashi Takehiro9,Tazuma Susumu2,Futamura Akihiko10,Uneno Yu11,Higashibeppu Naoki12,Kotani Joji13

Affiliation:

1. Department of Surgery, Mitsugi General Hospital, Onomichi, Hiroshima, Japan

2. Department of Internal Medicine, JA Onomichi General Hospital, Onomichi, Hiroshima, Japan

3. Center for Education in Medicine and Health Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

4. Department of Surgery, Tokyo Women’s Medical University Adachi Medical Center, Tokyo, Japan

5. Department of Surgery, Machida Municipal Hospital, Machida, Tokyo, Japan

6. Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan

7. Department of Gastroenterological Surgery, Osaka General Medical Center, Osaka, Japan

8. Department of Surgery, Hiroshima Red Cross Hospital and Atomic-Bomb Survivors’ Hospital, Hiroshima, Japan

9. Department of Gastroenterological Surgery, Kochi Health Sciences Center, Kouchi, Japan

10. Department of Pharmacy, Fujita Health University Nanakuri Memorial Hospital, Tsu, Mie, Japan

11. Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

12. Department of Anesthesia and Critical Care, Kobe City Medical Center Hospital, Kobe, Hyogo, Japan

13. Division of Disaster and Emergency Medicine, Department of Surgery Related Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.

Abstract

Introduction: Healthy eating and weight control are recommended for cancer survivors; however, dietary interventions are not routinely offered to them. This study aimed to assess the effects of dietary interventions on survival, nutritional status, morbidity, dietary changes, health-related quality of life (QOL), and clinical measures in cancer survivors. Methods: Searches were conducted from October 1, 2018 to November 21, 2011 in the Medline, EMBASE, CENTRAL, Emcare, and DARE electronic databases. We included randomized controlled trials (RCTs) that involved individuals diagnosed with cancer, excluding conference abstracts, case studies, other reviews, and meta-analyses, and screened the articles. Results: Eight studies were included in this meta-analysis. We observed significant improvements in QOL and clinical data in 3 of 6 studies and in one study, respectively, significant weight loss on anthropometry in 2 of 5 studies, and dietary improvement in 4 of 5 studies of adult cancer survivors. However, we did not observe any benefits of dietary intervention for cancer survivors with undernutrition. Discussion: Dietary interventions for adult cancer survivors might contribute to improving their nutritional status; however, further clarification requires a study that standardizes the intervention method. Furthermore, RCTs are required to determine the effects on cancer survivors with undernutrition.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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