Analysis of factors associated with patients’ global impression of change scores in inpatients with peripheral facial palsy: A retrospective study at a Korean Medicine Hospital

Abstract

The incidence of peripheral facial palsy is on the rise, with psychological issues influencing quality of life due to visible symptoms. Consequently, patient-reported outcome measures are critical in assessing the disease burden and the treatment efficacy of peripheral facial palsy from patients’ perspective. This study examines factors influencing patients’ global impression of change (PGIC) scores, a type of patient-reported outcome measure, in hospitalized patients with peripheral facial palsy. This retrospective study analyzed the electronic medical records of 200 patients with peripheral facial palsy who were admitted to the Korean Medicine Hospital, Kyung Hee University Medical Center from May 1, 2022 to April 30, 2023. Impact of demographic, electrophysiological, intervention, and clinical factors on PGIC scores were evaluated. Descriptive statistics showed that the length of hospitalization (P = .020), time from disease onset to hospitalization (P = .022), lacrimal disorders (P = .002), House–Brackmann (HB) grade evaluated at admission (P = .016) and at discharge (P < .001), improvement in HB-grade from admission to discharge (P = .002), and total facial disability index (FDI) score at discharge (P < .001) were significantly associated with PGIC scores. In multivariate logistic regression analysis, HB-grade at admission (OR: 13.89, 95% CI: 2.18–113.60), length of stay (OR: 0.27, 95% CI: 0.07–0.92), time from disease onset to hospitalization (OR: 5.55, 95% CI: 1.36–24. 77), tear-related symptoms (OR: 0.41, 95% CI: 0.17–0.96), total FDI score (OR: 0.45, 95% CI: 0.20–0.98), and greater improvement in HB-grade at discharge compared to admission (OR: 0.08, 95% CI: 0.02–0.31) were significantly associated with PGIC scores. Patients with milder initial disease severity, hospitalization period exceeding 7 days, shorter time from disease onset to hospitalization, improvement of lacrimal symptoms, total FDI score, and HB-grade between admission and discharge experienced more significant subjective improvement in peripheral facial palsy.