Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis-Reference-Cited by-同舟云学术

Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis

Published:2020-05-27 Issue:545 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Azouz Nurit P.¹^ORCID,Klingler Andrea M.¹,Pathre Purnima¹,Besse John A.¹^ORCID,Baruch-Morgenstern Netali Ben¹,Ballaban Adina Y.¹^ORCID,Osswald Garrett A.¹^ORCID,Brusilovsky Michael¹,Habel Jeff E.¹^ORCID,Caldwell Julie M.¹^ORCID,Ynga-Durand Mario A.¹²^ORCID,Abonia Pablo J.¹^ORCID,Hu Yueh-Chiang³^ORCID,Wen Ting¹,Rothenberg Marc E.¹^ORCID

Affiliation:

1. Division of Allergy and Immunology, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229-3026, USA.

2. Laboratorio de Inmunidad de Mucosas, Sección de Investigación y Posgrado, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City, Mexico.

3. Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229-3026, USA.

Abstract

Eosinophilic esophagitis is mediated by uncontrolled proteolytic activity of kallikrein 5 influencing the epithelial barrier and innate immunity.

Funder

NIH Office of the Director

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference83 articles.

1. Mechanisms of Disease of Eosinophilic Esophagitis

2. Pathophysiology of Eosinophilic Esophagitis

3. Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference