Identification of tetranectin-targeting monoclonal antibodies to treat potentially lethal sepsis-Reference-Cited by-同舟云学术

Identification of tetranectin-targeting monoclonal antibodies to treat potentially lethal sepsis

Published:2020-04-15 Issue:539 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Chen Weiqiang¹²^ORCID,Qiang Xiaoling¹²^ORCID,Wang Yongjun¹^ORCID,Zhu Shu¹²^ORCID,Li Jianhua¹,Babaev Ariella¹,Yang Huan¹²,Gong Jonathan¹²^ORCID,Becker Lance¹²^ORCID,Wang Ping¹²^ORCID,Tracey Kevin J.¹²^ORCID,Wang Haichao¹²^ORCID

Affiliation:

1. The Feinstein Institutes for Medical Research, Northwell Health, 350 Community Drive, Manhasset, NY 11030, USA.

2. Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 500 Hofstra Blvd., Hempstead, NY 11549, USA.

Abstract

An antibody strategy prevents harmful TN/HMGB1 interaction and resultant macrophage pyroptosis and immunosuppression in sepsis.

Funder

NIGMS

NCCIH

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference52 articles.

1. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

2. Sepsis: a roadmap for future research

3. The Pathophysiology and Treatment of Sepsis

4. HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

5. Reversing established sepsis with antagonists of endogenous high-mobility group box 1

Cited by 34 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The ASC inflammasome adapter governs SAA-derived protein aggregation in inflammatory amyloidosis;EMBO Molecular Medicine;2024-07-30

2. Therapeutic potential of procathepsin L-inhibiting and progesterone-entrapping dimethyl-β-cyclodextrin nanoparticles in treating experimental sepsis;Frontiers in Immunology;2024-03-14

3. Role of Histiocyte-Derived frHMGB1 as a Facilitator in Noncanonical Pyroptosis of Monocytes/Macrophages in Lethal Sepsis;The Journal of Infectious Diseases;2024-01-19

4. Immunosuppression in Sepsis: Biomarkers and Specialized Pro-Resolving Mediators;Biomedicines;2024-01-13

5. Insight into the function of tetranectin in human diseases: A review and prospects for tetranectin-targeted disease treatment;Heliyon;2024-01