Circulating transcripts in maternal blood reflect a molecular signature of early-onset preeclampsia

Author:

Munchel Sarah1ORCID,Rohrback Suzanne1ORCID,Randise-Hinchliff Carlo1,Kinnings Sarah1,Deshmukh Shweta1ORCID,Alla Nagesh1,Tan Catherine1ORCID,Kia Amirali1ORCID,Greene Grainger1ORCID,Leety Linda1ORCID,Rhoa Matthew1,Yeats Scott1ORCID,Saul Matthew1ORCID,Chou Julia1ORCID,Bianco Kimberley1ORCID,O’Shea Kevin1ORCID,Bujold Emmanuel2,Norwitz Errol3,Wapner Ronald4,Saade George5,Kaper Fiona1ORCID

Affiliation:

1. Illumina Inc., San Diego, CA 92122, USA.

2. Department of Obstetrics and Gynecology and Department of Social and Preventive Medicine, Faculty of Medicine, Université Laval, Quebec City, Quebec G1V 086, Canada.

3. Department of Obstetrics and Gynecology and the Mother Infant Research Institute, Tufts University School of Medicine, Boston, MA 02111, USA.

4. Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA.

5. Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX 77555, USA.

Abstract

Circulating transcripts reflect biologically relevant changes in early-onset severe preeclampsia and can accurately classify patient status.

Funder

Illumina

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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