Reconstitution of the gut microbiota of antibiotic-treated patients by autologous fecal microbiota transplant

Author:

Taur Ying1ORCID,Coyte Katharine123ORCID,Schluter Jonas1,Robilotti Elizabeth1,Figueroa Cesar1,Gjonbalaj Mergim1,Littmann Eric R.1ORCID,Ling Lilan1,Miller Liza14ORCID,Gyaltshen Yangtsho15ORCID,Fontana Emily1,Morjaria Sejal1ORCID,Gyurkocza Boglarka1ORCID,Perales Miguel-Angel1,Castro-Malaspina Hugo1ORCID,Tamari Roni1,Ponce Doris1,Koehne Guenther1,Barker Juliet1ORCID,Jakubowski Ann1,Papadopoulos Esperanza1,Dahi Parastoo1,Sauter Craig1,Shaffer Brian1,Young James W.167ORCID,Peled Jonathan1ORCID,Meagher Richard C.1ORCID,Jenq Robert R.8ORCID,van den Brink Marcel R. M.16ORCID,Giralt Sergio A.1ORCID,Pamer Eric G.1ORCID,Xavier Joao B.1

Affiliation:

1. Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

2. Department of Zoology, University of Oxford, Oxford, UK.

3. Division of Infectious Diseases and Division of Gastroenterology, Department of Medicine, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115, USA.

4. Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.

5. American Museum of Natural History, New York, NY 10024, USA.

6. Weill Cornell Medical College, New York, NY 10065, USA.

7. Rockefeller University, New York, NY 10065, USA.

8. University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Abstract

A randomized clinical trial demonstrates that autologous fecal microbiota transplant can reconstitute the gut microbiota of patients undergoing intensive antibiotic treatment.

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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