Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer-Reference-Cited by-同舟云学术

Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer

Published:2016-02-24 Issue:327 Volume:8 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Enriquez-Navas Pedro M.¹,Kam Yoonseok¹,Das Tuhin¹,Hassan Sabrina¹,Silva Ariosto¹,Foroutan Parastou¹,Ruiz Epifanio¹,Martinez Gary¹²,Minton Susan³,Gillies Robert J.¹⁴,Gatenby Robert A.¹⁴

Affiliation:

1. Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

2. Department of Physics, University of South Florida, Tampa, FL 33620, USA.

3. Department of Women’s Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

4. Cancer Biology and Evolution Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

Abstract

Using evolutionary principles to guide drug administration, monotherapy with paclitaxel can maintain prolonged stability of breast cancer in preclinical models.

Funder

James S. McDonnell Foundation

NIH

National Cancer Institute

Application of Evolutionary Principles to Maintain Cancer Control

NIH/NCI

NCI

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference35 articles.