Antioxidants can increase melanoma metastasis in mice-Reference-Cited by-同舟云学术

Antioxidants can increase melanoma metastasis in mice

Published:2015-10-07 Issue:308 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Le Gal Kristell¹²,Ibrahim Mohamed X.¹³,Wiel Clotilde¹³,Sayin Volkan I.²⁴,Akula Murali K.¹³,Karlsson Christin¹³,Dalin Martin G.¹³,Akyürek Levent M.²,Lindahl Per²⁴,Nilsson Jonas¹⁵,Bergo Martin O.¹³

Affiliation:

1. Sahlgrenska Cancer Center, University of Gothenburg, SE-405 30 Gothenburg, Sweden.

2. Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, SE-405 30 Gothenburg, Sweden.

3. Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, SE-405 30 Gothenburg, Sweden.

4. Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, SE-413 45 Gothenburg, Sweden.

5. Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, SE-405 30 Gothenburg, Sweden.

Abstract

Antioxidants increase migration and invasion of human melanoma cells and accelerate metastasis in an endogenous mouse model of malignant melanoma.

Funder

Swedish Cancer Society

Goran Gustafsson Foundation

Ingabritt and Arne Lundberg's Research Foundation

Knut and Alice Wallenberg Foundation

Swedish Research Council

Assar Gabrielsson Foundation

Swedish Children's Cancer Fund

BioCARE�a National Strategic Research Program