Host gene expression classifiers diagnose acute respiratory illness etiology-Reference-Cited by-同舟云学术

Host gene expression classifiers diagnose acute respiratory illness etiology

Published:2016-01-20 Issue:322 Volume:8 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Tsalik Ephraim L.¹²³,Henao Ricardo¹⁴,Nichols Marshall¹,Burke Thomas¹,Ko Emily R.¹⁵,McClain Micah T.¹³⁶,Hudson Lori L.¹,Mazur Anna¹,Freeman Debra H.¹³,Veldman Tim¹,Langley Raymond J.⁷,Quackenbush Eugenia B.⁸,Glickman Seth W.⁸,Cairns Charles B.⁸⁹,Jaehne Anja K.¹⁰,Rivers Emanuel P.¹⁰,Otero Ronny M.¹⁰,Zaas Aimee K.¹³,Kingsmore Stephen F.¹¹,Lucas Joseph¹,Fowler Vance G.³,Carin Lawrence¹⁴,Ginsburg Geoffrey S.¹,Woods Christopher W.¹³⁶

Affiliation:

1. Center for Applied Genomics and Precision Medicine, Department of Medicine, Duke University, Durham, NC 27708, USA.

2. Emergency Medicine Service, Durham Veteran’s Affairs Medical Center, Durham, NC 27705, USA.

3. Division of Infectious Diseases and International Health, Department of Medicine, Duke University, Durham, NC 27710, USA.

4. Department of Electrical and Computer Engineering, Duke University, Durham, NC 27708, USA.

5. Duke Regional Hospital, Department of Medicine, Duke University, Durham, NC 27710, USA.

6. Section for Infectious Diseases, Medicine Service, Durham Veteran’s Affairs Medical Center, Durham, NC 27705, USA.

7. Immunology Division, Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA.

8. Department of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.

9. Department of Emergency Medicine, University of Arizona Health Sciences Center, Tucson, AZ 85724, USA.

10. Department of Emergency Medicine, Henry Ford Hospital, Wayne State University, Detroit, MI 48202, USA.

11. Rady Pediatric Genomic and Systems Medicine Institute, Rady Children’s Hospital, San Diego, CA 92123, USA.

Abstract

Pathogen-specific host gene expression changes may combat inappropriate antibiotic use and emerging antibiotic resistance.

Funder

U.S. DARPA

NIH

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference41 articles.

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3. Outpatient antibiotic prescribing in the United States: 2000 to 2010

4. Antibiotic resistance: the perfect storm

5. Observations on spiraling empiricism: its causes, allure, and perils, with particular reference to antibiotic therapy

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