Development of a prosaposin-derived therapeutic cyclic peptide that targets ovarian cancer via the tumor microenvironment-Reference-Cited by-同舟云学术

Development of a prosaposin-derived therapeutic cyclic peptide that targets ovarian cancer via the tumor microenvironment

Published:2016-03-09 Issue:329 Volume:8 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Wang Suming¹²,Blois Anna¹²³,El Rayes Tina⁴⁵⁶,Liu Joyce F.⁷⁸,Hirsch Michelle S.⁹,Gravdal Karsten³¹⁰,Palakurthi Sangeetha¹¹,Bielenberg Diane R.¹²,Akslen Lars A.³¹⁰,Drapkin Ronny⁸⁹,Mittal Vivek⁴⁵⁶,Watnick Randolph S.¹²

Affiliation:

1. Vascular Biology Program, Boston Children’s Hospital, Boston, MA 02115, USA.

2. Department of Surgery, Harvard Medical School, Boston, MA 02115, USA.

3. Centre for Cancer Biomarkers (CCBIO), Department of Clinical Medicine, University of Bergen, NO-5020 Bergen, Norway.

4. Department of Cardiothoracic Surgery, Weill Cornell Medical College, New York, NY 10065, USA.

5. Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065, USA.

6. Neuberger Berman Lung Cancer Center, Weill Cornell Medical College, New York, NY 10065, USA.

7. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

8. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

9. Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.

10. Department of Pathology, Haukeland University Hospital, N-5021 Bergen, Norway.

11. Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

Abstract

A cyclic prosaposin-derived peptide targets ovarian cancer cells through the fatty acid translocase CD36.

Funder

Norwegian Cancer Society

Norwegian Research Council

NIH

Dr. Miriam and Sheldon G. Adelson Medical Research Foundation

Honorable Tina Brozman Foundation

Cornell Center on the Microenvironment and Metastasis

National Cancer Institute

Robert I. Goldman Foundation

Elsa U. Pardee Foundation

Boston Children's Hospital Technology Development Fund

Ovarian Cancer Research Fund

Pallotta Investigator Award

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference39 articles.

1. Ovarian Cancer Pathogenesis: A Model in Evolution

2. Coming into focus: the nonovarian origins of ovarian cancer

3. B. W. Stewart C. P. Wild World Cancer Report 2014 (WHO Press Geneva 2014).

4. Low drug resistance to both platinum and taxane chemotherapy on anin vitrodrug resistance assay predicts improved survival in patients with advanced epithelial ovarian, fallopian and peritoneal cancer

5. Clinical relevance of extent of extreme drug resistance in epithelial ovarian carcinoma

Cited by 50 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Visualization of nonsmall-cell lung cancer by near-infrared fluorescence imaging with tumor-targeting peptide ABT-510;Bioorganic Chemistry;2024-10

2. Thrombospondins: Conserved mediators and modulators of metazoan extracellular matrix;International Journal of Experimental Pathology;2024-09-12

3. Clinicopathological significance of CD36 expression in oral squamous cell carcinoma;2024-06-18

4. Interplay of CD36, autophagy, and lipid metabolism: insights into cancer progression;Metabolism;2024-06

5. Phase 1 dose expansion and biomarker study assessing first-in-class tumor microenvironment modulator VT1021 in patients with advanced solid tumors;Communications Medicine;2024-05-21