Amelioration of sepsis by TIE2 activation–induced vascular protection

Author:

Han Sangyeul12,Lee Seung-Jun23,Kim Kyung Eun1,Lee Hyo Seon1,Oh Nuri3,Park Inwon4,Ko Eun1,Oh Seung Ja1,Lee Yoon-Sook1,Kim David3,Lee Seungjoo3,Lee Dae Hyun3,Lee Kwang-Hoon1,Chae Su Young1,Lee Jung-Hoon1,Kim Su-Jin1,Kim Hyung-Chan1,Kim Seokkyun1,Kim Sung Hyun1,Kim Chungho5,Nakaoka Yoshikazu6,He Yulong7,Augustin Hellmut G.89,Hu Junhao8,Song Paul H.1,Kim Yong-In1,Kim Pilhan4,Kim Injune3,Koh Gou Young23

Affiliation:

1. Samsung Advanced Institute of Technology, Suwon, 446-712, Republic of Korea.

2. Center for Vascular Research, Institute for Basic Science, Daejeon 305-701, Republic of Korea.

3. Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Republic of Korea.

4. Graduate School of Nanoscience and Technology, KAIST, Daejeon 305-701, Republic of Korea.

5. School of Life Sciences and Technologies, Korea University, Seoul 136-701, Republic of Korea.

6. Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

7. Cyrus Tang Hematology Center, Soochow University, Suzhou 215123, China.

8. Division of Vascular Oncology and Metastasis, German Cancer Research Center Heidelberg (DKFZ-ZMBH Alliance), 69121 Heidelberg, Germany.

9. Department of Vascular Biology and Tumor Angiogenesis (CBTM), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.

Abstract

Vascular protection through TIE2 activation is a potential treatment strategy to ameliorate sepsis.

Funder

Samsung Advanced Institute of Technology

Institute for Basic Science

Ministry of Science, ICT & Future Planning

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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