Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females-Reference-Cited by-同舟云学术

Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females

Published:2016-04-13 Issue:334 Volume:8 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Ribas Vicent¹,Drew Brian G.¹,Zhou Zhenqi¹,Phun Jennifer¹,Kalajian Nareg Y.¹,Soleymani Teo¹,Daraei Pedram¹,Widjaja Kevin¹,Wanagat Jonathan²,de Aguiar Vallim Thomas Q.³,Fluitt Amy H.¹⁴,Bensinger Steven⁴,Le Thuc⁴⁵,Radu Caius⁴⁵,Whitelegge Julian P.⁶,Beaven Simon W.⁷,Tontonoz Peter⁷,Lusis Aldons J.³⁸,Parks Brian W.⁸,Vergnes Laurent⁸,Reue Karen⁸,Singh Harpreet⁹,Bopassa Jean C.⁹,Toro Ligia⁹,Stefani Enrico⁹,Watt Matthew J.¹⁰,Schenk Simon¹¹,Akerstrom Thorbjorn¹²,Kelly Meghan¹²,Pedersen Bente K.¹²,Hewitt Sylvia C.¹³,Korach Kenneth S.¹³,Hevener Andrea L.¹¹⁴

Affiliation:

1. Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.

2. Division of Geriatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

3. Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

4. Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

5. Ahmanson Translational Imaging Division, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

6. Pasarow Mass Spectrometry Laboratory and Neuropsychiatric Institute–Semel Institute for Neuroscience & Human Behavior, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

7. Howard Hughes Medical Institute and Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

8. Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

9. Department of Anesthesiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

10. Department of Physiology, Monash University, Clayton, Victoria 3800, Australia.

11. Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, CA 92093, USA.

12. Centre of Inflammation and Metabolism and Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Copenhagen 2200, Denmark.

13. Receptor Biology Section, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, Durham, NC 27709, USA.

14. UCLA Iris Cantor Women’s Health Research Center, Los Angeles, CA 90095, USA.

Abstract

ERα action in skeletal muscle is involved in the preservation of mitochondrial health and insulin sensitivity in female mice and can serve as a defense against metabolic disease in women.

Funder

Nuclear Receptor Signaling Atlas (NURSA) Data Source

UCLA Department of Medicine

UCLA Iris Cantor Women's Health Center_UCLA Clinical and Translational Science Institute

Spanish Ministry of Health

Australian National Health and Medical Research Council

UCLA Jonsson Comprehensive Cancer Center

Danish National Research Foundation (DNRF55)

TrygFonden

NIH National Center for Research Resources

NIH

Publisher