Human ESC–derived retinal epithelial cell sheets potentiate rescue of photoreceptor cell loss in rats with retinal degeneration-Reference-Cited by-同舟云学术

Human ESC–derived retinal epithelial cell sheets potentiate rescue of photoreceptor cell loss in rats with retinal degeneration

Published:2017-12-20 Issue:421 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Ben M’Barek Karim¹²³^ORCID,Habeler Walter¹²³^ORCID,Plancheron Alexandra¹²³^ORCID,Jarraya Mohamed⁴,Regent Florian¹²,Terray Angélique⁵,Yang Ying⁵⁶,Chatrousse Laure¹²³^ORCID,Domingues Sophie¹²³^ORCID,Masson Yolande¹²³^ORCID,Sahel José-Alain⁵⁶⁷⁸^ORCID,Peschanski Marc¹²³^ORCID,Goureau Olivier⁵^ORCID,Monville Christelle¹²^ORCID

Affiliation:

1. INSERM U861, I-Stem, Association Française contre les Myopathies (AFM), Institute for Stem Cell Therapy and Exploration of Monogenic Diseases, 91100 Corbeil-Essonnes, France.

2. UEVE U861, I-Stem, AFM, Institute for Stem Cell Therapy and Exploration of Monogenic Diseases, 91100 Corbeil-Essonnes, France.

3. CECS, I-Stem, AFM, Institute for Stem Cell Therapy and Exploration of Monogenic Diseases, 91100 Corbeil-Essonnes, France.

4. Banque de tissus humain, Hôpital Saint Louis, AP-HP Paris, France.

5. Institut de la Vision, Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, 75012 Paris, France.

6. CHNO des Quinze-Vingts, DHU Sight Restore, INSERM-DHOS CIC, 75012 Paris, France.

7. Fondation Ophtalmologique Adolphe de Rothschild, 75019 Paris, France.

8. Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

Abstract

Human ESC–derived retinal pigment epithelial cell sheets are more effective than cell suspensions at rescuing photoreceptor cell loss in rats with retinal dystrophy.

Funder

Association Francaise contre les Myopathies

Fondation de France

ANR

ERC Synergy

LABEX LIFESENSES

LABEX REVIVE

FRM

NeurATRIS

Ingestem

Publisher

American Association for the Advancement of Science (AAAS)