STING differentially regulates experimental GVHD mediated by CD8 versus CD4 T cell subsets-Reference-Cited by-同舟云学术

STING differentially regulates experimental GVHD mediated by CD8 versus CD4 T cell subsets

Published:2020-07-15 Issue:552 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Bader Cameron S.¹^ORCID,Barreras Henry¹,Lightbourn Casey O.¹^ORCID,Copsel Sabrina N.¹^ORCID,Wolf Dietlinde²^ORCID,Meng Jingjing³,Ahn Jeonghyun⁴,Komanduri Krishna V.¹²^ORCID,Blazar Bruce R.⁵^ORCID,Jin Lei⁶^ORCID,Barber Glen N.²⁴^ORCID,Roy Sabita²³^ORCID,Levy Robert B.¹²⁷^ORCID

Affiliation:

1. Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

2. Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

3. Department of Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

4. Department of Cell Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

5. Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN 55455, USA.

6. Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Florida, Gainesville, FL 32610, USA.

7. Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Abstract

STING differentially regulates experimental graft-versus-host disease mediated by distinct T cell subsets.

Funder

National Eye Institute

National Cancer Institute

Sylvester Comprehensive Cancer Center

Kalish Family Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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3. Donor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice

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