Near-infrared nerve-binding fluorophores for buried nerve tissue imaging

Author:

Wang Lei G.1ORCID,Barth Connor W.1ORCID,Kitts Catherine H.1ORCID,Mebrat Mubark D.1ORCID,Montaño Antonio R.1ORCID,House Broderick J.1ORCID,McCoy Meaghan E.1ORCID,Antaris Alexander L.2,Galvis S. N.2ORCID,McDowall Ian2ORCID,Sorger Jonathan M.2ORCID,Gibbs Summer L.134ORCID

Affiliation:

1. Biomedical Engineering Department, Oregon Health & Science University, Portland, OR 97201, USA.

2. Intuitive Surgical, Sunnyvale, CA 94086, USA.

3. Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97201, USA.

4. Center for Spatial Systems Biomedicine, Oregon Health & Science University, Portland, OR 97201, USA.

Abstract

Small-molecule near-infrared nerve contrast agents were developed to enable nerve visualization at depth, improving nerve-sparing during surgery.

Funder

National Institute of Biomedical Imaging and Bioengineering

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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