Biocompatible near-infrared quantum dots delivered to the skin by microneedle patches record vaccination

Author:

McHugh Kevin J.1ORCID,Jing Lihong12ORCID,Severt Sean Y.1ORCID,Cruz Mache1ORCID,Sarmadi Morteza13,Jayawardena Hapuarachchige Surangi N.1ORCID,Perkinson Collin F.4ORCID,Larusson Fridrik5ORCID,Rose Sviatlana1,Tomasic Stephanie1ORCID,Graf Tyler1ORCID,Tzeng Stephany Y.1,Sugarman James L.1ORCID,Vlasic Daniel6,Peters Matthew5ORCID,Peterson Nels5ORCID,Wood Lowell5ORCID,Tang Wen1,Yeom Jihyeon1ORCID,Collins Joe1ORCID,Welkhoff Philip A.7,Karchin Ari5,Tse Megan1ORCID,Gao Mingyuan2,Bawendi Moungi G.4ORCID,Langer Robert1ORCID,Jaklenec Ana1ORCID

Affiliation:

1. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.

2. Key Laboratory of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Bei Yi Jie 2, Zhong Guan Cun, Beijing 100190, China.

3. Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.

4. Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.

5. Global Good, Intellectual Ventures Laboratory, 14360 SE Eastgate Way, Bellevue, WA 98007, USA.

6. Independent consultant, 119 Kendall Rd, Lexington, MA 02421, USA ().

7. Institute for Disease Modeling, 3150 139th Ave. SE, Bellevue, WA 98005, USA.

Abstract

Near-infrared fluorescent microparticles administered to the skin via dissolvable microneedle patches can record vaccine delivery.

Funder

National Science Foundation

U.S. Department of Energy

National Institute of Biomedical Imaging and Bioengineering

Bill and Melinda Gates Foundation

National Natural Science Foundation of China

Youth Innovation Promotion Association CAS

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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