Lactation improves pancreatic β cell mass and function through serotonin production

Author:

Moon Joon Ho12ORCID,Kim Hyeongseok13ORCID,Kim Hyunki1ORCID,Park Jungsun1,Choi Wonsuk1,Choi Wongun1,Hong Hyun Jung4,Ro Hyun-Joo56ORCID,Jun Sangmi56,Choi Sung Hee2ORCID,Banerjee Ronadip R.7ORCID,Shong Minho4ORCID,Cho Nam Han8,Kim Seung K.9,German Michael S.10ORCID,Jang Hak Chul2ORCID,Kim Hail1ORCID

Affiliation:

1. Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.

2. Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.

3. Department of Biochemistry, College of Medicine, Chungnam National University, Daejeon 35015, Korea.

4. Research Center for Endocrine and Metabolic Diseases, Chungnam National University School of Medicine, Daejeon 35015, Korea.

5. Center for Research Equipment, Korea Basic Science Institute, Cheongju 28119, Korea.

6. Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon 34114, Korea.

7. Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Alabama School of Medicine, Birmingham, AL 35294, USA.

8. Department of Preventive Medicine, Ajou University School of Medicine, Suwon 16499, Korea.

9. Department of Developmental Biology and Stanford Diabetes Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA.

10. Diabetes Center, Hormone Research Institute and Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.

Abstract

Lactation benefits women’s metabolic health by improving pancreatic β cell mass and function through serotonin production in β cells.

Funder

National Institutes of Health

Larry L. Hillblom Foundation

National Research Foundation of Korea

National Research Council of Science and Technology

Health Fellowship Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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