PAPPA-mediated adipose tissue remodeling mitigates insulin resistance and protects against gestational diabetes in mice and humans-Reference-Cited by-同舟云学术

PAPPA-mediated adipose tissue remodeling mitigates insulin resistance and protects against gestational diabetes in mice and humans

Published:2020-11-25 Issue:571 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Rojas-Rodriguez Raziel¹²^ORCID,Ziegler Rachel¹,DeSouza Tiffany¹^ORCID,Majid Sana³^ORCID,Madore Aylin S.⁴^ORCID,Amir Nili⁴^ORCID,Pace Veronica A.³^ORCID,Nachreiner Daniel³^ORCID,Alfego David⁵^ORCID,Mathew Jomol⁵⁶^ORCID,Leung Katherine⁴,Moore Simas Tiffany A.⁴,Corvera Silvia¹^ORCID

Affiliation:

1. Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

2. Graduate School of Biomedical Sciences, University of Massachusetts Medical School, Worcester, MA 01605, USA.

3. Clinical Translational Research Pathway, University of Massachusetts Medical School, Worcester, MA 01605, USA.

4. Departments of Obstetrics and Gynecology, University of Massachusetts Medical School and UMass Memorial Healthcare, Worcester, MA 01605, USA.

5. Division of Data Sciences and Technology, IT, University of Massachusetts Medical School, Worcester, MA 01605, USA.

6. Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01605, USA.

Abstract

A signaling pathway involving the placenta and adipose tissue underlies the development of gestational diabetes.

Funder

National Institute of General Medical Sciences

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference104 articles.

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3. Predicting Future Diabetes in Latino Women With Gestational Diabetes: Utility of Early Postpartum Glucose Tolerance Testing

4. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis

5. Prediction of type 2 diabetes in women with a history of gestational diabetes using a genetic risk score

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