Oral, ultra–long-lasting drug delivery: Application toward malaria elimination goals

Author:

Bellinger Andrew M.123,Jafari Mousa1,Grant Tyler M.13,Zhang Shiyi1,Slater Hannah C.4,Wenger Edward A.5,Mo Stacy1,Lee Young-Ah Lucy1,Mazdiyasni Hormoz1,Kogan Lawrence1,Barman Ross1,Cleveland Cody16,Booth Lucas1,Bensel Taylor1,Minahan Daniel1,Hurowitz Haley M.1,Tai Tammy1,Daily Johanna7,Nikolic Boris8,Wood Lowell5,Eckhoff Philip A.5,Langer Robert1910,Traverso Giovanni1611

Affiliation:

1. Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

2. Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

3. Lyndra Inc., Watertown, MA 02472, USA.

4. Department of Infectious Disease Epidemiology, MRC (Medical Research Council) Centre for Outbreak Analysis and Modelling, Imperial College London, London, U.K.

5. Institute for Disease Modeling, Bellevue, WA 98005, USA.

6. Division of Gastroenterology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

7. Division of Infectious Diseases, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

8. Biomatics Capital, 1107 1st Avenue, Apartment 1305, Seattle, WA 98101, USA.

9. Media Lab, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

10. Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

11. Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Abstract

A newly developed platform capable of oral, ultra–long-acting drug delivery could be applied against the malaria vector in elimination programs.

Funder

Alexander von Humboldt-Stiftung Foundation

NIH

National Sciences and Engineering Research Council of Canada

Bill and Melinda Gates Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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