A green tea–triggered genetic control system for treating diabetes in mice and monkeys

Author:

Yin Jianli1ORCID,Yang Linfeng1ORCID,Mou Lisha2,Dong Kaili1,Jiang Jian1ORCID,Xue Shuai1ORCID,Xu Ying1,Wang Xinyi1ORCID,Lu Ying2,Ye Haifeng1ORCID

Affiliation:

1. Synthetic Biology and Biomedical Engineering Laboratory, Biomedical Synthetic Biology Research Center, Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Dongchuan Road 500, Shanghai 200241, China.

2. Shenzhen Xenotransplantation Medical Engineering Research and Development Center, Institute of Translational Medicine, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong 518035, China.

Abstract

A green tea–triggered genetic control system was developed for genome/epigenome editing, digital computations, and diabetes therapy in mice and monkeys.

Funder

National Natural Science Foundation of China

Science and Technology Commission of Shanghai Municipality

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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