Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition-Reference-Cited by-同舟云学术

Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition

Published:2020-04-29 Issue:541 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Akoumianakis Ioannis¹^ORCID,Badi Ileana¹^ORCID,Douglas Gillian¹^ORCID,Chuaiphichai Surawee¹,Herdman Laura¹^ORCID,Akawi Nadia¹^ORCID,Margaritis Marios¹^ORCID,Antonopoulos Alexios S.¹^ORCID,Oikonomou Evangelos K.¹^ORCID,Psarros Costas¹,Galiatsatos Nikolaos²^ORCID,Tousoulis Dimitris³^ORCID,Kardos Attila⁴,Sayeed Rana⁵^ORCID,Krasopoulos George⁵^ORCID,Petrou Mario⁵,Schwahn Uwe⁶^ORCID,Wohlfart Paulus⁶^ORCID,Tennagels Norbert⁶^ORCID,Channon Keith M.¹^ORCID,Antoniades Charalambos¹^ORCID

Affiliation:

1. Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.

2. Biochemistry Department, Hippokration General Hospital, Athens 115 27, Greece.

3. First Cardiology Clinic, Athens University Medical School, Athens 115 27, Greece.

4. Milton Keynes University Hospital NHS Foundation Trust and Faculty of Life Sciences, University of Buckingham, Buckingham MK6 5LD, UK.

5. Cardiothoracic Surgery Department, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 9DU, UK.

6. Sanofi Aventis Deutschland GmbH, Frankfurt D-65926, Germany.

Abstract

Vascular oxidative stress in human atherosclerosis is reversed by restoring vascular insulin sensitivity using a dipeptidyl peptidase 4 inhibitor.

Funder

National Institute for Health Research

British Heart Foundation

Sanofi Aventis Deutshcland GmbH

Oxford Biomedical Research Centre

Alexandros S Onassis Public Benefit Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference42 articles.

1. Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I

2. Impaired Vascular Redox Signaling in the Vascular Complications of Obesity and Diabetes Mellitus

3. Diverse regulation of AKT and GSK-3β by O-GlcNAcylation in various types of cells

4. Cardiovascular effects of basal insulins

5. Basal Insulin and Cardiovascular and Other Outcomes in Dysglycemia

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