Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria-Reference-Cited by-同舟云学术

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

Published:2018-06-27 Issue:447 Volume:10 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Lee Hyun Jae¹^ORCID,Georgiadou Athina²^ORCID,Walther Michael³,Nwakanma Davis³^ORCID,Stewart Lindsay B.⁴,Levin Michael²,Otto Thomas D.⁵^ORCID,Conway David J.⁴^ORCID,Coin Lachlan J.¹,Cunnington Aubrey J.²^ORCID

Affiliation:

1. Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia.

2. Section of Paediatrics, Imperial College, London W2 1PG, UK.

3. Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, P.O. Box 273, Fajara, The Gambia.

4. Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

5. Wellcome Trust Sanger Centre, Hinxton, Cambridge CB10 1SA, UK.

Abstract

Host and parasite RNA sequencing is combined with parasite load estimates to reveal mechanisms associated with human severe malaria.

Funder

Wellcome Trust

Medical Research Council

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference93 articles.

1. Resolving host–pathogen interactions by dual RNA-seq

2. Dual RNA-seq of pathogen and host

3. Malaria

4. Piecing Together the Puzzle of Severe Malaria

5. Severe malaria: what’s new on the pathogenesis front?

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