Therapeutic exercise attenuates neutrophilic lung injury and skeletal muscle wasting-Reference-Cited by-同舟云学术

Therapeutic exercise attenuates neutrophilic lung injury and skeletal muscle wasting

Published:2015-03-11 Issue:278 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Files D. Clark¹²,Liu Chun¹,Pereyra Andrea³⁴,Wang Zhong-Min³,Aggarwal Neil R.⁵,D’Alessio Franco R.⁵,Garibaldi Brian T.⁵,Mock Jason R.⁵,Singer Benjamin D.⁵,Feng Xin⁶,Yammani Raghunatha R.⁷,Zhang Tan³,Lee Amy L.¹,Philpott Sydney¹,Lussier Stephanie¹,Purcell Lina¹,Chou Jeff⁸,Seeds Michael¹²,King Landon S.⁵,Morris Peter E.¹²,Delbono Osvaldo³

Affiliation:

1. Department of Internal Medicine—Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

2. Wake Forest Critical Illness, Injury and Recovery Research Center, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

3. Department of Internal Medicine—Gerontology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

4. National Scientific and Technical Research Council (CONICET) and School of Medicine, National University of La Plata, 1900 La Plata, Argentina.

5. Division of Pulmonary and Critical Care Medicine, Johns Hopkins Asthma and Allergy Center, Baltimore, MD 21205, USA.

6. Department of Otolaryngology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

7. Department of Internal Medicine—Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

8. Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

Abstract

Exercise-induced modification of neutrophil chemokine signaling attenuates skeletal muscle wasting and limits lung injury in mice and patients with acute respiratory failure.

Funder

NIH

National Institute on Aging

American Heart Association

American Thoracic Society Foundation

Wake Forest School of Medicine

Claude D. Pepper Older Americans Independence Center

Department of Medicine

Parker B. Francis Foundation

Wake Forest Health Sciences Translational Science Institute

Publisher

American Association for the Advancement of Science (AAAS)