Comment on “A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk”-Reference-Cited by-同舟云学术

Comment on “A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk”

Published:2022-10-05 Issue:665 Volume:14 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Kivimäki Mika¹²^ORCID,Hingorani Aroon D.³⁴⁵⁶^ORCID,Lindbohm Joni V.¹²⁷

Affiliation:

1. Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.

2. Clinicum, University of Helsinki, Helsinki FIN-00014, Finland.

3. Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.

4. UCL British Heart Foundation Research Accelerator, London WC1E 6BT, UK.

5. UCL National Institute of Health Research Biomedical Research Centre, London W1T 7DN, UK.

6. Health Data Research UK, London NW1 2BE, UK.

7. Broad Institute, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA.

Abstract

A 27-protein signature has been proposed to predict cardiovascular disease, but its applicability in clinical decision-making remains unclear.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference8 articles.

1. A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk

2. A. D. Hingorani J. Gratton C. Finan A. F. Schmidt R. Patel R. Sofat V. Kuan C. Langenberg H. Hemingway J. K. Morris N. J. Wald Polygenic scores in disease prediction: Evaluation using the relevant performance metrics. medRxiv preprint (2022); https://doi.org/10.1101/2022.02.18.22271049.

3. Cohort Profile: The Whitehall II study

4. Plasma protein patterns as comprehensive indicators of health

5. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines;Goff D. C.;Circulation,2014

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