Precision adjuvants for pediatric vaccines-Reference-Cited by-同舟云学术

Precision adjuvants for pediatric vaccines

Published:2024-09-04 Issue:763 Volume:16 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Singh Anjali¹^ORCID,Boggiano César¹^ORCID,Yin Dwight E.¹^ORCID,Polakowski Laura¹^ORCID,Majji Sai P.²,Leitner Wolfgang W.³^ORCID,Levy Ofer⁴⁵⁶^ORCID,De Paris Kristina⁷^ORCID

Affiliation:

1. Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA.

2. Maternal and Pediatric Infectious Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20817, USA.

3. Division of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA.

4. Precision Vaccines Program, Department of Pediatrics, Boston Children’s Hospital, Boston, MA 02115, USA.

5. Harvard Medical School, Boston, MA 02115, USA.

6. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

7. Department of Microbiology and Immunology, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.

Abstract

Elucidating optimal vaccine adjuvants for harnessing age-specific immune pathways to enhance magnitude, breadth, and durability of immunogenicity remains a key gap area in pediatric vaccine design. A better understanding of age-specific adjuvants will inform precision discovery and development of safe and effective vaccines for protecting children from preventable infectious diseases.

Publisher

American Association for the Advancement of Science (AAAS)

Link

https://www.science.org/doi/pdf/10.1126/scitranslmed.abq7378

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