Bone CLARITY: Clearing, imaging, and computational analysis of osteoprogenitors within intact bone marrow-Reference-Cited by-同舟云学术

Bone CLARITY: Clearing, imaging, and computational analysis of osteoprogenitors within intact bone marrow

Published:2017-04-26 Issue:387 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Greenbaum Alon¹^ORCID,Chan Ken Y.¹^ORCID,Dobreva Tatyana¹^ORCID,Brown David¹^ORCID,Balani Deepak H.²,Boyce Rogely³,Kronenberg Henry M.²,McBride Helen J.³^ORCID,Gradinaru Viviana¹^ORCID

Affiliation:

1. Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

2. Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

3. Comparative Biology and Safety Sciences, Amgen, Thousand Oaks, CA 91320, USA.

Abstract

Bone clearing and light-sheet microscopy enables visualization and quantification of fluorescent single cells in intact bone.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference49 articles.

1. Building strong bones: molecular regulation of the osteoblast lineage

2. Discoveries, drugs and skeletal disorders

3. Skeletal stem cells

4. Advances in treatment of achondroplasia and osteoarthritis

5. The bone marrow niche for haematopoietic stem cells

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