Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 and CA19-9 blood markers

Author:

Kim Jungsun1ORCID,Bamlet William R.2,Oberg Ann L.2ORCID,Chaffee Kari G.2ORCID,Donahue Greg1,Cao Xing-Jun3ORCID,Chari Suresh4,Garcia Benjamin A.3,Petersen Gloria M.5,Zaret Kenneth S.1ORCID

Affiliation:

1. Institute for Regenerative Medicine, Department of Cell and Developmental Biology, Abramson Cancer Center (Tumor Biology Program), Perelman School of Medicine, University of Pennsylvania, 9-131 Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, PA 19104–5157, USA.

2. Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

3. Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

4. Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.

5. Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

Abstract

THBS2 and CA19-9 markers in human blood improve detection of pancreatic ductal adenocarcinoma.

Funder

U.S. Department of Defense

NIH Office of the Director

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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