Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail-Reference-Cited by-同舟云学术

Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail

Published:2017-09-20 Issue:408 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Julg Boris¹²^ORCID,Liu Po-Ting¹^ORCID,Wagh Kshitij³^ORCID,Fischer William M.³^ORCID,Abbink Peter¹^ORCID,Mercado Noe B.¹^ORCID,Whitney James B.¹²,Nkolola Joseph P.¹,McMahan Katherine¹^ORCID,Tartaglia Lawrence J.¹^ORCID,Borducchi Erica N.¹,Khatiwada Shreeya¹,Kamath Megha¹^ORCID,LeSuer Jake A.¹^ORCID,Seaman Michael S.¹^ORCID,Schmidt Stephen D.⁴^ORCID,Mascola John R.⁴^ORCID,Burton Dennis R.²⁵^ORCID,Korber Bette T.³^ORCID,Barouch Dan H.¹²^ORCID

Affiliation:

1. Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.

2. Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139, USA.

3. Los Alamos National Laboratory, Los Alamos, NM 87545, USA.

4. Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

5. The Scripps Research Institute, La Jolla, CA 92037, USA.

Abstract

A combination of HIV-1–specific broadly neutralizing antibodies is necessary to protect rhesus monkeys against a mixed SHIV challenge.

Funder

National Institute of Allergy and Infectious Diseases

amfAR, The Foundation for AIDS Research

Ragon Institute