Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy-Reference-Cited by-同舟云学术

Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy

Published:2018-01-03 Issue:422 Volume:10 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Bourgeois-Daigneault Marie-Claude¹²^ORCID,Roy Dominic Guy¹²^ORCID,Aitken Amelia Sadie¹²,El Sayes Nader¹²,Martin Nikolas Tim¹²,Varette Oliver¹²^ORCID,Falls Theresa¹^ORCID,St-Germain Lauren Elizabeth¹,Pelin Adrian¹²^ORCID,Lichty Brian Dennis³^ORCID,Stojdl David Francis²⁴,Ungerechts Guy¹^ORCID,Diallo Jean-Simon¹²^ORCID,Bell John Cameron¹²^ORCID

Affiliation:

1. Centre for Innovative Cancer Research, Ottawa Hospital Research Institute, Ottawa K1H 8L6, Canada.

2. Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa K1H 8M5, Canada.

3. Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton L8S 4K1, Canada.

4. Children’s Hospital of Eastern Ontario Research Institute, Ottawa K1H 8L1, Canada.

Abstract

Maraba virus treatment before surgery for triple-negative breast cancer promotes antitumor immunity.

Funder

Canadian Cancer Society Research Institute

Terry Fox Foundation

Ontario Institute for Cancer Research

BioCanRx

Canadian institute of Health Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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5. The blockade of immune checkpoints in cancer immunotherapy

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