Blocking α 4 β 7 integrin delays viral rebound in SHIV SF162P3 -infected macaques treated with anti-HIV broadly neutralizing antibodies-Reference-Cited by-同舟云学术

Blocking α 4 β 7 integrin delays viral rebound in SHIV SF162P3 -infected macaques treated with anti-HIV broadly neutralizing antibodies

Published:2021-08-18 Issue:607 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Frank Ines¹^ORCID,Cigoli Mariasole¹^ORCID,Arif Muhammad S.²^ORCID,Fahlberg Marissa D.³^ORCID,Maldonado Stephanie¹,Calenda Giulia¹,Pegu Amarendra⁴^ORCID,Yang Eun Sung⁴^ORCID,Rawi Reda⁴,Chuang Gwo-Yu⁴,Geng Hui⁴^ORCID,Liu Cuiping⁴,Zhou Tongqing⁴^ORCID,Kwong Peter D.⁴^ORCID,Arthos James⁵^ORCID,Cicala Claudia⁵^ORCID,Grasperge Brooke F.³^ORCID,Blanchard James L.³^ORCID,Gettie Agegnehu⁶,Fennessey Christine M.⁷^ORCID,Keele Brandon F.⁷^ORCID,Vaccari Monica³^ORCID,Hope Thomas J.²^ORCID,Fauci Anthony S.⁵^ORCID,Mascola John R.⁴^ORCID,Martinelli Elena¹²^ORCID

Affiliation:

1. Center for Biomedical Research, Population Council, New York, NY, USA.

2. Department of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

3. Tulane National Primate Research Center, Tulane University, Covington, LA, USA.

4. Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.

5. Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

6. Aaron Diamond AIDS Research Center, Rockefeller University, New York, NY, USA.

7. AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.

Abstract

Broadly neutralizing antibodies and an anti-α 4 β 7 monoclonal antibody prolong viral load control in SHIV SF162P3 -infected macaques.

Funder

National Institutes of Health

National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference55 articles.

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