Enhanced SARS-CoV-2 neutralization by dimeric IgA-Reference-Cited by-同舟云学术

Enhanced SARS-CoV-2 neutralization by dimeric IgA

Published:2021-01-20 Issue:577 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Wang Zijun¹^ORCID,Lorenzi Julio C. C.¹^ORCID,Muecksch Frauke²^ORCID,Finkin Shlomo¹^ORCID,Viant Charlotte¹,Gaebler Christian¹^ORCID,Cipolla Melissa¹^ORCID,Hoffmann Hans-Heinrich³^ORCID,Oliveira Thiago Y.¹^ORCID,Oren Deena A.⁴^ORCID,Ramos Victor¹^ORCID,Nogueira Lilian¹^ORCID,Michailidis Eleftherios³^ORCID,Robbiani Davide F.⁵^ORCID,Gazumyan Anna¹^ORCID,Rice Charles M.³,Hatziioannou Theodora²,Bieniasz Paul D.²⁶,Caskey Marina¹^ORCID,Nussenzweig Michel C.¹⁶^ORCID

Affiliation:

1. Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

2. Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.

3. Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.

4. Structural Biology Resource Center, The Rockefeller University, New York, NY 10065, USA.

5. Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.

6. Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA.

Abstract

Human dimeric IgA antibodies are potent neutralizers of SARS-CoV-2.

Funder

National Institutes of Health

Howard Hughes Medical Institute

National Center for Advancing Translational Sciences

George Mason University

European Commission

G. Harold and Leila Y. Mathers Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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