A portable magnetofluidic platform for detecting sexually transmitted infections and antimicrobial susceptibility

Author:

Trick Alexander Y.1ORCID,Melendez Johan H.2,Chen Fan-En1ORCID,Chen Liben3ORCID,Onzia Annet4ORCID,Zawedde Aidah4,Nakku-Joloba Edith5,Kyambadde Peter6ORCID,Mande Emmanuel4ORCID,Matovu Joshua4,Atuheirwe Maxine4ORCID,Kwizera Richard4ORCID,Gilliams Elizabeth A.27ORCID,Hsieh Yu-Hsiang8ORCID,Gaydos Charlotte A.2ORCID,Manabe Yukari C.24,Hamill Matthew M.27ORCID,Wang Tza-Huei1239ORCID

Affiliation:

1. Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.

2. Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

3. Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.

4. Infectious Diseases Institute, Makerere University, Kampala, Uganda.

5. School of Public Health, Makerere University, Kampala, Uganda.

6. AIDS Control Program, Division of Sexually Transmitted Infections, Ministry of Health, Kampala, Uganda.

7. Sexual Health Clinics, Baltimore City Health Department, Baltimore, MD 21205, USA.

8. Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

9. Institute for NanoBiotechnology, Johns Hopkins University, Baltimore, MD 21218, USA.

Abstract

A portable magnetofluidic platform integrates nucleic acid purification and PCR to rapidly detect the pathogen causing gonorrhea in clinical samples.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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