Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases-Reference-Cited by-同舟云学术

Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases

Published:2022-01-05 Issue:626 Volume:14 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Dixit Deobrat¹^ORCID,Prager Briana C.¹²³^ORCID,Gimple Ryan C.¹²^ORCID,Miller Tyler E.⁴^ORCID,Wu Qiulian¹⁵^ORCID,Yomtoubian Shira¹,Kidwell Reilly L.¹^ORCID,Lv Deguan¹⁵^ORCID,Zhao Linjie¹⁵^ORCID,Qiu Zhixin¹⁵^ORCID,Zhang Guoxin¹^ORCID,Lee Derrick¹⁵,Park Donglim Esther¹^ORCID,Wechsler-Reya Robert J.⁶^ORCID,Wang Xiuxing¹^ORCID,Bao Shideng³⁷^ORCID,Rich Jeremy N.¹⁵^ORCID

Affiliation:

1. Division of Regenerative Medicine, Department of Medicine, University of California, San Diego, San Diego, CA 92037, USA.

2. Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA.

3. Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44106, USA.

4. Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.

5. University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, PA 15232, USA.

6. Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.

7. Department of Cancer Biology, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44106, USA.

Abstract

DPY30 is an in vivo–specific dependency in glioblastoma that regulates phosphodiesterases and angiogenesis in the hypoxic tumor microenvironment.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference61 articles.

1. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

2. Targeting glioma stem cells through combined BMI1 and EZH2 inhibition

3. Identification of human brain tumour initiating cells

4. Brain Tumor Stem Cells Remain in Play

5. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Epigenetics and environmental health;Frontiers of Medicine;2024-05-28

2. DPY30 knockdown suppresses colorectal carcinoma progression via inducing Raf1/MST2-mediated apoptosis;Heliyon;2024-02

3. cAMP-PKA/EPAC signaling and cancer: the interplay in tumor microenvironment;Journal of Hematology & Oncology;2024-01-17

4. PDE4B promotes the progression of gastric cancer via the PI3K/AKT/MYC pathway and immune infiltration;American Journal of Cancer Research;2024

5. DPY30 promotes colorectal carcinoma metastasis by upregulating ZEB1 transcriptional expression;Cancer Cell International;2023-12-19