Alloantigen-specific type 1 regulatory T cells suppress through CTLA-4 and PD-1 pathways and persist long-term in patients

Author:

Chen Pauline P.1ORCID,Cepika Alma-Martina1ORCID,Agarwal-Hashmi Rajni1ORCID,Saini Gopin12ORCID,Uyeda Molly J.13,Louis David M.4ORCID,Cieniewicz Brandon1ORCID,Narula Mansi1,Amaya Hernandez Laura C.3ORCID,Harre Nicholas1ORCID,Xu Liwen156,Thomas Benjamin Craig1,Ji Xuhuai6ORCID,Shiraz Parveen5ORCID,Tate Keri M.7ORCID,Margittai Dana7ORCID,Bhatia Neehar7ORCID,Meyer Everett15ORCID,Bertaina Alice12ORCID,Davis Mark M.489ORCID,Bacchetta Rosa12ORCID,Roncarolo Maria Grazia123ORCID

Affiliation:

1. Division of Hematology, Oncology, Stem Cell Transplantation, and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.

2. Center for Definitive and Curative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

3. Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

4. Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA.

5. Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

6. Stanford Functional Genomics Facility, Stanford University School of Medicine, Stanford, CA 94305, USA.

7. Stanford Laboratory for Cell and Gene Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

8. Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.

9. Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

Abstract

Type 1 regulatory T cells suppress alloreactive immune cells after adoptive transfer in a CTLA-4 and PD-1–mediated manner.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Cited by 44 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3