T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals-Reference-Cited by-同舟云学术

T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals

Published:2021-04-21 Issue:590 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Bilich Tatjana¹²³^ORCID,Nelde Annika¹²³^ORCID,Heitmann Jonas S.¹³^ORCID,Maringer Yacine¹²³^ORCID,Roerden Malte²³⁴^ORCID,Bauer Jens¹²^ORCID,Rieth Jonas¹²,Wacker Marcel¹²^ORCID,Peter Andreas⁵,Hörber Sebastian⁵^ORCID,Rachfalski David¹,Märklin Melanie¹³^ORCID,Stevanović Stefan²³⁶^ORCID,Rammensee Hans-Georg²³⁶^ORCID,Salih Helmut R.¹³⁶^ORCID,Walz Juliane S.¹²³⁷^ORCID

Affiliation:

1. Clinical Collaboration Unit Translational Immunology, German Cancer Consortium (DKTK), Department of Internal Medicine, University Hospital Tübingen, 72076 Tübingen, Germany.

2. Institute for Cell Biology, Department of Immunology, University of Tübingen, 72076 Tübingen, Germany.

3. Cluster of Excellence iFIT (EXC2180) “Image-Guided and Functionally Instructed Tumor Therapies”, University of Tübingen, 72076 Tübingen, Germany.

4. Department of Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tübingen, 72076 Tübingen, Germany.

5. Institute for Clinical Chemistry and Pathobiochemistry, Department for Diagnostic Laboratory Medicine, University Hospital Tübingen, 72076 Tübingen, Germany.

6. German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Partner Site Tübingen, 72076 Tübingen, Germany.

7. Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and Robert Bosch Center for Tumor Diseases (RBCT), 70376 Stuttgart, Germany.

Abstract

Longitudinal analysis identifies SARS-CoV-2 peptide targets of durable memory T cell responses in COVID-19 convalescent individuals.

Funder

Wilhelm Sander-Stiftung

Deutsche Forschungsgemeinschaft

Bundesministerium für Bildung und Forschung

José Carreras Leukämie-Stiftung

Deutsches Konsortium für Translationale Krebsforschung

Deutsche Forschungsgemeinschaft under Germany’s Excellence Strategy

Fortüne Program of the University of Tübingen