Mitochondrial metabolic reprogramming controls the induction of immunogenic cell death and efficacy of chemotherapy in bladder cancer-Reference-Cited by-同舟云学术

Mitochondrial metabolic reprogramming controls the induction of immunogenic cell death and efficacy of chemotherapy in bladder cancer

Published:2021-01-06 Issue:575 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Oresta Bianca¹^ORCID,Pozzi Chiara²^ORCID,Braga Daniele¹^ORCID,Hurle Rodolfo³,Lazzeri Massimo³,Colombo Piergiuseppe⁴,Frego Nicola³,Erreni Marco⁵^ORCID,Faccani Cristina¹,Elefante Grazia⁴,Barcella Matteo⁶^ORCID,Guazzoni Giorgio³⁷,Rescigno Maria¹⁷^ORCID

Affiliation:

1. Humanitas Clinical and Research Center–IRCCS, via Manzoni 56, 20089 Rozzano (Milan), Italy.

2. Department of Experimental Oncology, European Institute of Oncology–IRCCS, via Ripamonti 435, 20141 Milan, Italy.

3. Department of Urology, Humanitas Clinical and Research Center–IRCCS, via Manzoni 56, 20089 Rozzano (Milan), Italy.

4. Department of Pathology, Humanitas Clinical and Research Center–IRCCS, via Manzoni 56, 20089 Rozzano (Milan), Italy.

5. Unit of Advanced Optical Microscopy, Humanitas Clinical and Research Center–IRCCS, via Manzoni 56, 20089 Rozzano (Milan), Italy.

6. Dipartimento di Scienze della Salute, Università degli Studi di Milano, 20142 Milan, Italy.

7. Humanitas University, Department of Biomedical Sciences, via Rita Levi Montalcini 4, 20090 Pieve Emanuele (Milan), Italy.

Abstract

Immunogenic cell death induced through metabolic reprogramming by intravesical chemotherapy in bladder cancer is associated with treatment success.

Funder

European Research Council

Ministero della Salute

Associazione Italiana per la Ricerca sul Cancro

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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5. The EGFR-specific antibody cetuximab combined with chemotherapy triggers immunogenic cell death

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