Toward robust mammography-based models for breast cancer risk

Author:

Yala Adam12ORCID,Mikhael Peter G.12ORCID,Strand Fredrik34ORCID,Lin Gigin5ORCID,Smith Kevin67,Wan Yung-Liang5ORCID,Lamb Leslie8,Hughes Kevin9,Lehman Constance8ORCID,Barzilay Regina12ORCID

Affiliation:

1. Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

2. Jameel Clinic, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

3. Breast Radiology Unit, Department of Imaging and Physiology, Karolinska University Hospital, 17164 Solna, Sweden.

4. Department of Oncology-Pathology, Karolinska Institute, 17164 Solna, Sweden.

5. Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.

6. School of Electrical Engineering and Computer, KTH Royal Institute of Technology, 10044 Stockholm, Sweden.

7. Science for Life Laboratory, 17165 Solna, Sweden.

8. Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

9. Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Abstract

An algorithm to predict breast cancer risk, Mirai, outperforms clinical risk models across test cohorts from the United States, Sweden, and Taiwan.

Funder

Susan G. Komen for the Cure

Breast Cancer Research Foundation

Chang Gung Medical Foundation

Quanta Computing

MIT J-Clinic

Stockholm Läns Landsting HMT

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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