Bioadhesive hydrogels demonstrating pH-independent and ultrafast gelation promote gastric ulcer healing in pigs-Reference-Cited by-同舟云学术

Bioadhesive hydrogels demonstrating pH-independent and ultrafast gelation promote gastric ulcer healing in pigs

Published:2020-08-26 Issue:558 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Xu Xiayi¹^ORCID,Xia Xianfeng²³^ORCID,Zhang Kunyu¹⁴^ORCID,Rai Aliza⁵,Li Zhuo¹,Zhao Pengchao¹^ORCID,Wei Kongchang¹⁶^ORCID,Zou Li⁷,Yang Boguang¹^ORCID,Wong Wai-Ki¹,Chiu Philip Wai-Yan¹³⁵^ORCID,Bian Liming¹⁸^ORCID

Affiliation:

1. Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR 999077, China.

2. Department of Endoscopy, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510000, China.

3. Chow Yuk Ho Technology Centre for Innovative Medicine, The Chinese University of Hong Kong, Hong Kong SAR 999077, China.

4. Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.

5. Department of Surgery, Institute of Digestive Disease, State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong SAR 999077, China.

6. Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Biomimetic Membranes and Textiles, Lerchenfeldstrasse 5, CH-9014 St. Gallen, Switzerland.

7. Department of Orthpaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR 999077, China.

8. The Chinese University of Hong Kong Shenzhen Research Institute, Shenzhen 518000, China.

Abstract

Bioadhesive hydrogel with ultrafast gelation independent of environmental pH is endoscopically delivered to enhance gastric ulcer healing.

Funder

National Natural Science Foundation of China

Research Grants Council, University Grants Committee, Hong Kong

Health and Medical Research Fund

Innovation and Technology Fund

Publisher

American Association for the Advancement of Science (AAAS)

Subject