The Human Vaccines Project: A roadmap for cancer vaccine development

Author:

Romero Pedro1,Banchereau Jacques2,Bhardwaj Nina3,Cockett Mark4,Disis Mary L.5,Dranoff Glenn6,Gilboa Eli7,Hammond Scott A.8,Hershberg Robert9,Korman Alan J.10,Kvistborg Pia11,Melief Cornelis12,Mellman Ira13,Palucka A. Karolina214,Redchenko Irina15,Robins Harlan16,Sallusto Federica17,Schenkelberg Theodore18,Schoenberger Stephen19,Sosman Jeffrey20,Türeci Özlem21,Van den Eynde Benoît222324,Koff Wayne25,Coukos George1

Affiliation:

1. Ludwig Cancer Research at University of Lausanne, 1066 Epalinges, Switzerland.

2. The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032, USA.

3. Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

4. Bristol-Myers Squibb, Wallingford, CT06492, USA.

5. University of Washington School of Medicine, Seattle, WA 98109-4714, USA.

6. Novartis Institutes for Biomedical Research, Cambridge, MA 02139, USA.

7. Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA.

8. MedImmune, Gaithersburg, MD 20878, USA.

9. Celgene Immuno-Oncology Center of Excellence, 1616 Eastlake Avenue, Suite 500, Seattle, WA 98102, USA.

10. Bristol-Myers Squibb, Biologics Discovery California, Redwood City, CA 94063, USA.

11. Netherlands Cancer Institute, 1066CX Amsterdam, Netherlands.

12. ISA Pharmaceuticals & Leiden University Medical Center, 2333 ZA Leiden, Netherlands.

13. Genentech, San Francisco, CA 94080, USA.

14. Baylor Institute for Immunology Research, Dallas, TX 75204, USA.

15. Oxford University, Oxford OX3 7DQ, UK.

16. Adaptive Biotechnologies, Fred Hutchinson Cancer Research Center, Seattle, WA 98102, USA.

17. Institute for Research in Biomedicine, Università della Svizzera italiana, 6500 Bellinzona, Switzerland.

18. West Monument Consulting, 1906 R Street NW Street 11, Washington, DC 20009, USA.

19. Center for Personalized Cancer Immunotherapy, La Jolla Institute for Allergy and Immunology & UCSD Moores Cancer Center, La Jolla, San Diego, CA 92037, USA.

20. Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, TN 37232, USA.

21. CI3 Cluster for Individualized Immunotherapy, Kupferbergterasse 17-19, 55131 Mainz, Germany.

22. Ludwig Institute for Cancer Research, Brussels branch, Brussels, BRU 1200, Belgium.

23. Université Catholique de Louvain, Avenue Hippocrate 10, 1200 Woluwe-Saint-Lambert, Belgium.

24. University of Oxford, Nuffield Department of Medicine, Ludwig Institute for Cancer Research, Old Road Campus Research Building, Oxford OX3 7DQ, UK.

25. International AIDS Vaccines Initiative, 125 Broad Street, 9th Floor, New York, NY 10004, USA.

Abstract

A concerted international effort is necessary to achieve clinically effective cancer vaccines.

Funder

Robert Wood Johnson Foundation

Glaxo Smith Kline

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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