Robust classification of bacterial and viral infections via integrated host gene expression diagnostics

Author:

Sweeney Timothy E.12,Wong Hector R.34,Khatri Purvesh12

Affiliation:

1. Stanford Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA.

2. Biomedical Informatics Research, Stanford University School of Medicine, Stanford, CA 94305, USA.

3. Division of Critical Care Medicine, Cincinnati Children’s Hospital Medical Center and Cincinnati Children’s Research Foundation, Cincinnati, OH 45223, USA.

4. Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.

Abstract

An 18-gene panel distinguishes patients with bacterial and viral infections as well as those with inflammation not caused by infection.

Funder

Stanford Child Health Research Institute Young Investigator

Society of University Surgeons

Bill & Melinda Gates Foundation

National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference67 articles.

1. Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour

2. Vital signs: Improving antibiotic use among hospitalized patients;Fridkin S.;Morb. Mortal. Wkly. Rep.,2014

3. Antibiotic Prescription Rates for Acute Respiratory Tract Infections in US Ambulatory Settings

4. J. Andrews in 9th International Conference on Typhoid and Invasive NTS Disease (Bali Indonesia 2015).

5. National Strategy and Action Plan for Combating Antibiotic Resistant Bacteria (Nova Publishers New York 2015).

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