IgA-coated E. coli enriched in Crohn’s disease spondyloarthritis promote T H 17-dependent inflammation-Reference-Cited by-同舟云学术

IgA-coated E. coli enriched in Crohn’s disease spondyloarthritis promote T H 17-dependent inflammation

Published:2017-02-08 Issue:376 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Viladomiu Monica¹,Kivolowitz Charles¹,Abdulhamid Ahmed¹,Dogan Belgin²,Victorio Daniel¹,Castellanos Jim G.¹,Woo Viola¹,Teng Fei³,Tran Nhan L.³,Sczesnak Andrew⁴,Chai Christina¹,Kim Myunghoo⁵,Diehl Gretchen E.⁵,Ajami Nadim J.⁵,Petrosino Joseph F.⁵,Zhou Xi K.⁶,Schwartzman Sergio⁷,Mandl Lisa A.⁷,Abramowitz Meira⁸,Jacob Vinita⁸,Bosworth Brian⁹,Steinlauf Adam⁸,Scherl Ellen J.⁸,Wu Hsin-Jung Joyce³,Simpson Kenneth W.²,Longman Randy S.¹⁸

Affiliation:

1. Jill Roberts Institute for Research in Inflammatory Bowel Disease (IBD), Weill Cornell Medicine, New York, NY 10021, USA.

2. College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

3. Department of Immunobiology, University of Arizona, Tucson, AZ 85719, USA.

4. Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94709, USA.

5. Alkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.

6. Division of Biostatistics and Epidemiology, Weill Cornell Medical College, New York, NY 10065, USA.

7. Hospital for Special Surgery, New York, NY 10021, USA.

8. Jill Roberts Center for IBD, Weill Cornell Medicine, New York, NY 10021, USA.

9. Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.

Abstract

IgA-reactive E. coli in Crohn’s disease–associated spondyloarthritis link mucosal immunity and systemic inflammation.

Funder

NIH

Crohn's and Colitis Foundation of America

NSF

Southwest Clinic and Research Institute Fund

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference70 articles.

1. Crohn’s Disease: Evolution, Epigenetics, and the Emerging Role of Microbiome-Targeted Therapies

2. R. S. Longman E. J Scherl in Medical Therapy of Ulcerative Colitis G. Lichtenstein Ed. (Springer Science 2015).

3. Enteropathic Spondyloarthritis: From Diagnosis to Treatment

4. Complications and Sequelae of Chronic Ulcerative Colitis

5. The evolution of spondyloarthropathies in relation to gut histology. I. Clinical Aspects;Mielants H.;J. Rheumatol.,1995

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