P-selectin is a nanotherapeutic delivery target in the tumor microenvironment-Reference-Cited by-同舟云学术

P-selectin is a nanotherapeutic delivery target in the tumor microenvironment

Published:2016-06-29 Issue:345 Volume:8 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Shamay Yosi¹,Elkabets Moshe²³,Li Hongyan⁴,Shah Janki¹,Brook Samuel²,Wang Feng⁴⁵,Adler Keren¹⁶,Baut Emily¹⁷,Scaltriti Maurizio²⁸,Jena Prakrit V.¹,Gardner Eric E.¹⁹,Poirier John T.¹⁷¹⁰,Rudin Charles M.¹⁷¹⁰,Baselga José²¹⁰,Haimovitz-Friedman Adriana⁴,Heller Daniel A.¹⁷

Affiliation:

1. Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

2. Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

3. The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.

4. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

5. Department of Oncology, Albert Einstein Cancer Center, Albert Einstein College of Medicine, New York, NY 10461, USA.

6. Brandeis University, Waltham, MA 02453, USA.

7. Weill Cornell Medical College, New York, NY 10065, USA.

8. Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

9. Pharmacology Graduate Training Program, Johns Hopkins University, Baltimore, MD 21287, USA.

10. Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Abstract

P-selectin–targeted nanoparticles deliver chemotherapy to tumors, particularly when combined with radiation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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